发明名称 THIOLACTONES AS NAALADASE INHIBITORS
摘要 This invention provides new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, inhibiting angiogenesis, effecting a TGF-² activity or a neuronal activity, and treating a glutamate abnormality, a compulsive disorder, neuropathy, pain, a prostate disease, cancer, Huntington's disease, diabetes, a retinal disorder or glaucoma.
申请公布号 PT1599461(E) 申请公布日期 2009.07.20
申请号 PT20040716834T 申请日期 2004.03.03
申请人 EISAI CORPORATION OF NORTH AMERICA 发明人 BARBARA S. SLUSHER;TAKASHI TSUKAMOTO
分类号 C07D335/02;A61K31/38;A61K31/381;A61K31/382;A61K31/407;A61P25/00;C07D335/06;C07D495/04;C07D498/02 主分类号 C07D335/02
代理机构 代理人
主权项
地址