NANO-BIOCHIP USED FOR REGISTRATION OF PROTEINS AND ALBUMINOUS COMPLEXES, WAY OF ITS RECEPTION AND WAY OF REGISTRATION OF PROTEINS AND ALBUMINOUS COMPLEXES WITH USE OF CATHETER MICROSCOPY

摘要

FIELD: medicine. ^ SUBSTANCE: invention concerns medicine, in particular to medical diagnostics. A nano-biochip for registration of proteins and albuminous complexes and a way of its reception is offered. As a biochip substrate a non-stratified material, for example polycarbonate or polystyrene with a relief grid, is used and then the surface is leveled by means of a die providing equal surface with the size of roughnesses not more than 1 mm; after that updating and immobilisation of the molecules-probes capable to cooperate with investigated proteins and albuminous complexes on a surface of the chip specifically is carried out. ^ EFFECT: way allows to raise reliability of the received biochip at the expense of exception of its stratification and to raise reliability of diagnostics at the expense of rising of registration sensitivity of specific proteins and albuminous complexes. ^ 12 cl, 2 dwg, 1 ex