发明名称 |
MXA AS AN ANTIVIRAL DRUG AND AS A TARGET FOR IDENTIFICATION OF ANTIVIRAL DRUGS FOR DNA VIRUS INFECTIONS |
摘要 |
The invention features methods and compositions for use in a screening assay to identify agents having antiviral activity against a DNA virus by assessing the effect of a candidate agent upon alternative splicing of MxA, or by assessing the effect of a candidate agent on production of a variant form of MxA protein. The invention also provides methods for enhancing resistance of cells to infection by a DNA virus by providing for elevated MxA and/or by providing for reduced production of variant MxA protein.
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申请公布号 |
WO2007111628(A3) |
申请公布日期 |
2009.04.16 |
申请号 |
WO2006US27382 |
申请日期 |
2006.07.14 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;KU, CHIA-CHI;ARVIN, ANN M. |
发明人 |
KU, CHIA-CHI;ARVIN, ANN M. |
分类号 |
C12Q1/70;A01N63/00;A61K39/395;C12P21/02;C12P21/04 |
主分类号 |
C12Q1/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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