发明名称 MOLECULAR MARKERS FOR CANCER PROGNOSIS
摘要 The invention is predicated on the finding that the gene expression level of two genes, GAPDH and RPL37A, already exhibits a powerful predictive power for assessing the outcome of a neoplastic or cancerous disease. The invention relates to a method for predicting an outcome of a patient suffering from or at risk of developing a neoplastic disease, said method comprising the steps of: a) obtaining a biological sample from said patient; b) quantif iably determining the gene expression level of GAPDH or RPL37A and at least one further housekeeping gene, wherein the expression level of GAPDH or RPL37A is determined in relation to the expression level of the at least one further housekeeping gene; c) arriving at a prediction by means of a mathematical discriminate function.
申请公布号 WO2009047062(A2) 申请公布日期 2009.04.16
申请号 WO2008EP61752 申请日期 2008.09.05
申请人 SIEMENS HEALTHCARE DIAGNOSTICS GMBH;STROPP, UDO;VON TOERNE, CHRISTIAN;WIRTZ, RALPH 发明人 STROPP, UDO;VON TOERNE, CHRISTIAN;WIRTZ, RALPH
分类号 C12Q1/68;G01N33/574 主分类号 C12Q1/68
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