发明名称 |
PAN CANCER ONCOLYTIC VECTORS AND METHODS OF USE THEREOF |
摘要 |
Replication-competent adenoviral vectors which selectively replicate in cancer cells are provided. The replication-competent viral vectors comprise an E2F responsive promoter and/or a telomerase promoter operatively linked to an adenoviral coding region. The replication-competent adenoviral vectors effectively replicate in a variety of types of cancer cells and find broad utility in the treatment of cancer.
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申请公布号 |
US2009099125(A1) |
申请公布日期 |
2009.04.16 |
申请号 |
US20080327936 |
申请日期 |
2008.12.04 |
申请人 |
CELL GENESYS, INC. |
发明人 |
YU DECHAO;LI YUANHAO |
分类号 |
A61K31/7088;A61K48/00;C12N5/02;C12N7/00;C12N15/63;C12N15/861 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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