发明名称 |
SHORT INTERFERING RNA AS AN ANTIVIRAL AGENT FOR HEPATITIS C |
摘要 |
Hepatitis C virus (HCV) is a major cause of chronic liver disease and affects over 270 million individuals worldwide. The HCV genome is a single-stranded RNA that functions as both a messenger RNA and replication template, making it an attractive target for the study of RNA interference. Double-stranded short interfering RNA (siRNA) molecules designed to target the HCV genome are disclosed herein.
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申请公布号 |
US2009099124(A1) |
申请公布日期 |
2009.04.16 |
申请号 |
US20080326508 |
申请日期 |
2008.12.02 |
申请人 |
AMGEN INC. |
发明人 |
JAYASENA SUMEDHA;RICHARDSON CHRISTOPHER DONALD |
分类号 |
A61K31/7105;A61K38/00;A61P31/14;C07H21/02;C12N5/10;C12N15/113;C12N15/85 |
主分类号 |
A61K31/7105 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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