发明名称 |
FUSION POLYPEPTIDE COMPRISING S-ANTIGEN REPEAT UNITS |
摘要 |
<p>The present invention relates to a fusion polypeptide comprising a) at least one fragment of the Plasmodium falciparum S-antigen or a variant thereof, wherein the fragment comprises one or a plurality of Plasmodium falciparum S-antigen repeat unit(s) or variant(s) thereof and b) at least one antigen different from the S-antigen. The present invention also relates to a pharmaceutical composition comprising that fusion polypeptide as well as to the use thereof for the treatment or prevention of an autoimmune disease, an allergic reaction, a transplantation-related complication, e.g. graft rejection or 'graft vs. host disease', and another inflammatory disease and a method for treatment or prevention of said conditions.</p> |
申请公布号 |
WO2009047009(A1) |
申请公布日期 |
2009.04.16 |
申请号 |
WO2008EP08660 |
申请日期 |
2008.10.13 |
申请人 |
MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN;HUMBOLDT-UNIVERSITAET ZU BERLIN;FALK, KIRSTEN;ROETZSCHKE, OLAF;LUCIUS, RICHARD |
发明人 |
FALK, KIRSTEN;ROETZSCHKE, OLAF;LUCIUS, RICHARD |
分类号 |
C07K14/445;A61K39/002;C12N15/62 |
主分类号 |
C07K14/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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