发明名称 TETRAHYDRO-PYRAZOLO-PYRIDINE THIOETHER MODULATORS OF CATHEPSIN S
摘要 Tetrahydro-pyrazolo-pyridine thioether compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.
申请公布号 US2009099157(A1) 申请公布日期 2009.04.16
申请号 US20080031551 申请日期 2008.02.14
申请人 AMERIKS MICHAEL K;ARIENTI KRISTEN L;EDWARDS JAMES P;GRICE CHERYL A;JONES TODD K;LEE-DUTRA ALICE;LIU JING;MANI NEELAKANDHA S;NEFF DANIELLE K;WICKBOLDT ALVAH T;WIENER JOHN J M 发明人 AMERIKS MICHAEL K.;ARIENTI KRISTEN L.;EDWARDS JAMES P.;GRICE CHERYL A.;JONES TODD K.;LEE-DUTRA ALICE;LIU JING;MANI NEELAKANDHA S.;NEFF DANIELLE K.;WICKBOLDT ALVAH T.;WIENER JOHN J.M.
分类号 A61K31/551;A61K31/437;A61K31/5377;A61P9/10;A61P37/08;C07D471/04 主分类号 A61K31/551
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