发明名称 |
METHODS AND COMPOSITIONS FOR THERAPEUTIC TREATMENT |
摘要 |
Methods and compositions are described for the modulation of central nervous system and/or fetal effects of calcineurin inhibitors. Methods and compositions are described for the modulation of efflux transporter activity to increase the efflux of calcineurin inhibitors out of a physiological compartment and into an external environment. In particular, the methods and compositions disclosed herein provide for the increase of efflux transporter activity at Blood-Tissue, blood-CSF and placental-maternal barriers to increase the efflux of calcineurin inhibitor from physiological compartments, including central nervous system and fetal compartments. |
申请公布号 |
WO2008083160(A3) |
申请公布日期 |
2009.04.16 |
申请号 |
WO2007US88827 |
申请日期 |
2007.12.26 |
申请人 |
LIMERICK BIOPHARMA, INC.;ROBBINS, WENDYE |
发明人 |
ROBBINS, WENDYE |
分类号 |
A61K31/352;A61K31/436;A61K31/7048 |
主分类号 |
A61K31/352 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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