Disclosed are conjugates and complexes that include a folate receptor ligand and one or more therapeutic molecules, such as onconase or a variant thereof such as rapLR1. The conjugates and complexes may be useful as primary therapeutic agents, which may be administered with additional therapeutic or diagnostic agents. Also disclosed are kits that include the conjugates and complexes.
申请公布号
WO2005069994(A3)
申请公布日期
2009.04.16
申请号
WO2005US02193
申请日期
2005.01.24
申请人
IMMUNOMEDICS, INC.;HANSEN, HANS, J.;MCBRIDE, WILLIAM, J.;GOLDENBERG, DAVID, M.;ROSSI, EDMUND, A.;CHANG, CHIEN-HSING, KEN
发明人
HANSEN, HANS, J.;MCBRIDE, WILLIAM, J.;GOLDENBERG, DAVID, M.;ROSSI, EDMUND, A.;CHANG, CHIEN-HSING, KEN