<p>This invention relates to an oramucosal pharmaceutical dosage form in the form of a wafer. The wafer comprises a porous, hydroscopic, muco-adhesive polymeric matrix with at least one desired pharmaceutically active compound added thereto. The polymer is selected from a number of polymers having different dissolution rates and, in use when taken orally, the matrix adheres to an oramucosal surface to dissolve over a predetermined period of time to release the pharmaceutically active compound. The invention also extends to a method of manufacturing an oramucosal pharmaceutical dosage form in the form of a wafer which involves freeze drying or lyophilisation.</p>
申请公布号
WO2007034287(A3)
申请公布日期
2009.04.16
申请号
WO2006IB02585
申请日期
2006.09.19
申请人
UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG;PATEL, RUPAL;PILLAY, VINESS;DANCKWERTS, MICHAEL, PAUL
发明人
PATEL, RUPAL;PILLAY, VINESS;DANCKWERTS, MICHAEL, PAUL