USE OF QUATERNARY PYRIDINIUM SALTS FOR RADIOPROTECTION

摘要

A method for the treatment or prevention of a cell or tissue damage in a living subject due to the exposure to ionizing radiation is provided, which comprises administration to said subject of a quaternary pyridinium salt of formula (I) wherein R' is H, OH, CONH2 or COCH3, R" is H or CH3, R'" is H or CH3, and X- is a pharmaceutically acceptable counterion, in an amount sufficient to inhibit radiation-induced damage.