PHOTODYNAMIC THERAPY PROCESS AND PHOTOSENSITIZER COMPOSITIONS

摘要

Use of a photosensitizer composition in the manufacture of a medicament for photodynamic therapy and a process for photodynamic therapy are provided along with a photosensitizer composition suitable for the use and the process. The photosensitizer composition comprises at least one photoactive ingredient in a chemically reduced state. According to the use, the photosensitizer composition having at least one photoactive ingredient in a chemically reduced state is provided. The photosensitizer composition is applied to tissue or other substrate such that the at least one photoactive ingredient is at or travels to a location adjacent a target medium and the at least one photoactive ingredient is then altered to a photoactive state. The at least one photoactive ingredient is then exposed to light energy for assisting in inhibiting at least one pathogen at the target medium. The prefered photosensitizer is methylene blue. It is preferably reduced by ascorbic acid.