发明名称 |
RECOMBINANT HOST FOR PRODUCING L-ASPARAGINASE II |
摘要 |
<p>The invention provides a recombinant Escherichia coli host cell for producing an Escherichia coli-asparaginase II enzyme. The host cell includes an Escherichia coli chromosome and at least one copy of a recombinant extrachromosomal vector, wherein the recombinant extrachromosomal vector encodes the L-asparaginase II enzyme, wherein the host cell chromosome also encodes the same L-asparaginase II enzyme, and wherein the host chromosome does not encode any other isoform of L-asparaginase II.</p> |
申请公布号 |
EP2046369(A2) |
申请公布日期 |
2009.04.15 |
申请号 |
EP20070840229 |
申请日期 |
2007.06.08 |
申请人 |
ENZON PHARMACEUTICALS, INC. |
发明人 |
FILPULA, DAVID R.;WANG, MAOLIANG |
分类号 |
A61K38/46;A61P35/00;C07H21/04;C12N1/21;C12N9/82;C12N15/63;C12P1/04 |
主分类号 |
A61K38/46 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|