发明名称 |
TREATMENT OF EMPHYSEMA USING RAR SELECTIVE RETINOID ANTAGONISTS |
摘要 |
This invention provides the use of RAR.gamma. selective agonists for the manufacture of a medicament containing one or more such agonists for the treatment of emphysema and other diseases associated with alveolar damage. In another aspect, this invention provides the use of RAR agonists, preferably a RAR.gamma. selectiv e agonist for the manufacture of medicaments for promoting tropoelastin gene expression and alveolar matrix repair.
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申请公布号 |
CA2387844(C) |
申请公布日期 |
2009.04.14 |
申请号 |
CA20002387844 |
申请日期 |
2000.10.13 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
KLAUS, MICHAEL;BELLONI, PAULA NANETTE |
分类号 |
A61K31/00;A61K45/00;A61K31/192;A61K31/195;A61K31/196;A61K31/202;A61K31/235;A61K31/24;A61P11/00;A61K31/352;A61K31/353;A61K31/355;A61K31/44;A61P43/00;C07C57/42;C07D311/58 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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