发明名称 |
Immune-modulating peptide |
摘要 |
Disclosed are peptides having SEQ ID NOs: 1 to 24 that induce superoxide generation by human monocytes or neutrophils; that induce an intracellular calcium increase by human peripheral blood monocytes or neutrophils; binds to formyl peptide receptor or formyl peptide receptor-like 1; that induce chemotactic migration of human monocytes or neutrophils in vitro; that induce degranulation in formyl peptide receptor expressing cells or formyl peptide receptor-like 1 expressing cells; that stimulate extracellular signal regulated protein kinase phosphorylation via activation of formyl peptide receptor or formyl peptide receptor-like 1; or that stimulate Akt phosphorylation via activation of formyl peptide receptor or formyl peptide receptor-like 1.
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申请公布号 |
US7517857(B2) |
申请公布日期 |
2009.04.14 |
申请号 |
US20050317924 |
申请日期 |
2005.12.23 |
申请人 |
POSCO;POSTECH FOUNDATION |
发明人 |
RYU SUNG-HO;SUH PANN-GHILL;BAE YOE-SIK;SONG JI-YOUNG |
分类号 |
A61K38/06;A61K38/07;A61K38/08;C07K5/083;C07K5/107;C07K5/11;C07K7/06 |
主分类号 |
A61K38/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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