发明名称 Solubilized topoisomerase poisons
摘要 The invention provides compounds of formula I: wherein A, B, W, Y, Z, and R1 have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I, and therapeutic methods for treating cancer using compounds of formula I.
申请公布号 US7517883(B2) 申请公布日期 2009.04.14
申请号 US20050210456 申请日期 2005.08.24
申请人 RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 发明人 LAVOIE EDMOND J.;RUCHELMAN ALEXANDER L.;LIU LEROY F.
分类号 C07D491/147;A61K31/4375;A61K31/4738;A61K31/4985;A61K31/5025;A61K31/503;A61P17/06;A61P31/04;A61P31/10;A61P31/12;A61P33/02;A61P35/00;A61P43/00;C07D487/14;C07D491/14;C07D491/22 主分类号 C07D491/147
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