发明名称 N-[HETEROARYL(PIPERIDINE-2-YL)METHYL]BENZAMIDE DERIVATIVES AND APPLICATION IN THERAPY
摘要 FIELD: chemistry. ^ SUBSTANCE: invention refers to new compounds of general formula (I): (I) where: R1 represents either direct or branched (C1-C7)alkyl, or (C2-C4)alkenyl; R2 represents piridinyl, thienyl, thiazol; R3 represents one or more substitutes chosen from halogen atoms and following groups; trifluoromethyl, direct or branched (C1-C6)alkyl; as free base or additive salt with acid. Additionally, the invention concerns medical product, pharmaceutical composition, and application. ^ EFFECT: production of new biologically active compounds active to specific inhibitors of glycine glyt 1 and/or glyt 2 carriers. ^ 6 cl, 2 ex, 1 tbl
申请公布号 RU2351596(C2) 申请公布日期 2009.04.10
申请号 RU20060116887 申请日期 2004.10.15
申请人 SANOFI-AVENTIS 发明人 DARGAZANLI ZHIAD;EHSTENN-BUTU ZHENEV'EV;MEDESKO FLORANS;RENON MARIJA-KARMEN
分类号 A61K31/445;A61P25/00;C07D401/06;C07D409/06;C07D417/06 主分类号 A61K31/445
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