Thermal Coefficient Driven Drug Pellet Size For Ophthalmic Injection

摘要

A method of injecting a mixture into an eye includes: providing the mixture in a dispensing chamber with an air gap located between the mixture and an interior surface of a dispensing chamber housing, when the mixture and dispensing chamber housing are near room temperature; bringing the dispensing chamber housing and mixture to a temperature range at which the mixture expands and is in a more liquid state; maintaining air in a needle after the mixture expands and prior to an injection; and injecting the air in the needle and the mixture into the eye.