USE OF THE SEROLOGICAL ASSAY OF THE CYTOKINE B-LYMPHOCYTE STIMULATOR (BLYS) FOR THE DIAGNOSIS, PROGNOSIS AND THE SCREENING OF THERAPEUTIC EFFICACY IN IMMUNE-RELATED DISEASES INCLUDING ORGAN-SPECIFIC AUTOIMMUNE DISEASES AND TRANSFUSION REACTIONS

摘要

Use of the assay in the serum of the cytokine B-Lymphocyte Stimulator (BLyS) for the diagnosis, prognosis and screening of therapeutic efficacy in the course of immune-mediated diseases including organ-specific autoimmune diseases (such as celiac disease and autoimmune thyroiditis) and / or transfusion reactions and / or IgA deficiency in a patient that includes an initial step of taking a sample of blood from the patient, a step of analyzing the blood sample to determine the concentration of cytokine BLyS, a step of comparing the BLyS levels determined in the previous step and one or more reference values of concentration of cytokine BLyS, a step of identifying a significant deviation between the determined concentration of cytokine BLyS and the reference values of concentration of cytokine BLyS indicated in the previous step and a step of assigning a diagnosis and / or prognosis and / or therapeutic effectiveness with respect to the immune-mediated diseases mentioned above, based on the previous steps.