发明名称 |
METHODS AND COMPOSITIONS FOR MALARIA PROPHYLAXIS |
摘要 |
A composition for preventing malaria infection including a steric inhibitor of circumsporozoite protein cleavage. A pharmaceutical composition for preventing malaria infection including a steric inhibitor and a pharmaceutical carrier. A method of malaria infection prophylaxis including the step of administering an effective amount of the composition of the present invention. A method of malaria prophylaxis by sterically inhibiting circumsporozoite protein processing or by directly inhibiting a protease of a sporozoite from binding to its target. Methods of preventing sporozoite cell invasion or preventing circumsporozoite processing through steric or direct inhibition.
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申请公布号 |
US2009092619(A1) |
申请公布日期 |
2009.04.09 |
申请号 |
US20070866738 |
申请日期 |
2007.10.03 |
申请人 |
SINNIS PHOTINI;COPPI ALIDA;NARDIN ELIZABETH |
发明人 |
SINNIS PHOTINI;COPPI ALIDA;NARDIN ELIZABETH |
分类号 |
A61K39/395;C07K16/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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