Nucleic acid reporters and methods of their use are provided. The nucleic acid reporters include molecular beacons modified with protein transduction domains to facilitate translocation of the nucleic acid reporter across cellular membranes. The nucleic acid reporters are also optionally modified with a targeting signal to direct the nucleic acid reporter to a specific cell, tissue, organ, intracellular region, organelle or vesicle.
申请公布号
WO2005021712(A3)
申请公布日期
2009.04.09
申请号
WO2004US20232
申请日期
2004.06.25
申请人
GEORGIA TECH RESEARCH CORPORATION;BAO, GANG;NITIN, NITIN;NIE, SHUMING;KIM, GLORIA, J.
发明人
BAO, GANG;NITIN, NITIN;NIE, SHUMING;KIM, GLORIA, J.