This invention encompasses for an isolated Bacillus phage AP50 that has one or more nucleotide substitutions in the phage genome, whereby the one or more nucleotide substitutions increase lytic activity of the phage. In addition, the invention encompasses for proteins expressed by the phages, compositions containing the proteins and/or the phage as well as methods of using the Bacillus phage AP50 to test for the presence of B. anthracis.
申请公布号
WO2009045581(A2)
申请公布日期
2009.04.09
申请号
WO2008US67089
申请日期
2008.06.16
申请人
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.;THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY;READ, TIMOTHY;SOZHAMANNAN, SHANMUGA