发明名称 |
COMPOSITION AND METHOD FOR IN VITRO PRESERVATION OF CORNEAL TISSUES |
摘要 |
A corneal storage solution which maintains cell density and cell viability of corneas stored in vitro for a period of greater than four days up to about two weeks is provided. The solution contains a buffered, balanced, nutrient and electrolyte aqueous solution, at least one colloidal osmotic agent, a phenolic antioxidant compound, a non-lactate-generating substrate, a thiol-containing compound, insulin, and at least one antibiotic. A method for in vitro storage and preservation of the viability of human corneal endothelial cells for subsequent use includes the steps of removing a cornea from an eye globe and placing the cornea in the above corneal storage solution. |
申请公布号 |
WO2006110552(A3) |
申请公布日期 |
2009.04.09 |
申请号 |
WO2006US13077 |
申请日期 |
2006.04.06 |
申请人 |
CLEO COSMETIC AND PHARMACEUTICAL CO., LLC;SOLL, DAVID, B. |
发明人 |
SOLL, DAVID, B.;RUIZ-WHITE, INEZ, A.;SMITH, TERESITA, M. |
分类号 |
A01N1/02 |
主分类号 |
A01N1/02 |
代理机构 |
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代理人 |
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地址 |
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