发明名称 ANTISENSE MODULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR 4 EXPRESSION
摘要 Antisense compounds, compositions and methods are provided for modulating the expression of fibroblast growth factor receptor 4 (FGFR4). The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding fibroblast growth factor receptor 4. Methods of using these compounds for modulation of fibroblast growth factor receptor 4 expression and for treatment of diseases associated with expression of fibroblast growth factor receptor 4 are provided.
申请公布号 CA2701128(A1) 申请公布日期 2009.04.09
申请号 CA20082701128 申请日期 2008.10.01
申请人 ISIS PHARMACEUTICALS, INC. 发明人 BHANOT, SANJAY;JAIN, RAVI;YU, XING-XIAN;FREIER, SUSAN M.
分类号 C12N15/113;A61K31/7088;A61P3/00;A61P25/18;C07H21/04;C07K14/71;C12N15/63 主分类号 C12N15/113
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