发明名称 |
ANTISENSE MODULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR 4 EXPRESSION |
摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of fibroblast growth factor receptor 4 (FGFR4). The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding fibroblast growth factor receptor 4. Methods of using these compounds for modulation of fibroblast growth factor receptor 4 expression and for treatment of diseases associated with expression of fibroblast growth factor receptor 4 are provided. |
申请公布号 |
CA2701128(A1) |
申请公布日期 |
2009.04.09 |
申请号 |
CA20082701128 |
申请日期 |
2008.10.01 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
BHANOT, SANJAY;JAIN, RAVI;YU, XING-XIAN;FREIER, SUSAN M. |
分类号 |
C12N15/113;A61K31/7088;A61P3/00;A61P25/18;C07H21/04;C07K14/71;C12N15/63 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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