FERTILITY ENHANCEMENT USING LIPID CARRIERS AND BIOACTIVE MOLECULES
摘要
The invention relates to a composition and method for enhancing fertilization. Fertilization enhancement is achieved by effectively delivering bioactive molecules with a lipid anchor (GPI-linked proteins) to the surface of epididymal or ejaculated sperm. The process may be facilitated or promoted in the presence of Clusterin/ApoJ, a well-known lipid carrier. The acquisition of these molecules, such as Sperm Adhesion Molecule 1 (SPAM1) can significantly impact sperm maturation and function.
申请公布号
WO2008054773(A3)
申请公布日期
2009.04.09
申请号
WO2007US22984
申请日期
2007.10.31
申请人
UNIVERSITY OF DELAWARE;DELEON, PATRICIA, A.;GRIFFITHS, GENEVIEVE, S.