| 摘要 |
Tools and methods are suited for cardiac pacing of right and left ventricles from a lead in the right ventricle, to facilitate synchronous contractions. Aspects involve pacing by delivering pulses to a cardiac site for improving function measured by QRS width, fractionation, late LV activation timing, mechanical synchronicity of the free wall and septal wall, or effective throughput/pressure. Aspects include determining a pacing threshold, beyond the capture threshold, to improve heart function; delivering pulses of opposite polarity; bi-ventricular pacing from a lead in the right ventricle; delivering pulses of opposite polarity at a site near the His bundle; electrode-based His pacing, without penetrating the myocardium; generating multiple pacing profiles including pulses of opposite polarity and another pacing profile; delivering a pacing profile to generate a synchronous contraction of the septal wall and free wall of the LV; and treating LBBB by pacing near the His bundle. |
