ADHESIVE PREPARATION

摘要

The invention provides an adhesive preparation comprising an elastic support and an adhesive layer laminated on at least one surface of the support. The elastic support is composed of a crimped woven fabric with stockinette stitch on both sides. The adhesive layer contains methyl salicylate in an amount of 10% by mass or more based on the total mass of the layer, and the water vapor transmission rate of the entire adhesive preparation measured at a temperature of 40°C and a relative humidity of 90% is 1 to 350 g/m224hr. When the application amount of the adhesive layer is set to 50 to 300 g/m2 and the adhesive preparation is applied to the human skin for 8 hours such that the contact area is 280cm2, the average ± standard deviation of AUC0-24 of the methyl salicylate in plasma is in the range of 3.0 to 60.0 nghr/mL, and the average ± standard deviation of AUC0-24 of salicylic acid being a metabolite of the methyl salicylate in plasma is in the range of 5000 to 13000 nghr/mL.