| 发明名称 |
N-HETEROCYCLIC BIARYL CARBOXAMIDES AS CCR RECEPTOR ANTAGONISTS |
| 摘要 |
The invention is concerned with novel biaryl derivatives of Formula (I), wherein Formula (A), m, R1, R2, R3, X1, X2 and X3 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR-2 receptor, CCR-5 receptor and/or CCR-3 receptor and can be used as medicaments.
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| 申请公布号 |
CA2700691(A1) |
申请公布日期 |
2009.04.09 |
| 申请号 |
CA20082700691 |
申请日期 |
2008.09.22 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
AEBI, JOHANNES;BINGGELI, ALFRED;GREEN, LUKE;HARTMANN, GUIDO;MAERKI, HANS P.;MATTEI, PATRIZIO;RICKLIN, FABIENNE;ROCHE, OLIVIER |
| 分类号 |
C07D401/04;A61K31/454;A61K31/4545;A61K31/506;A61K31/551;A61P9/00;A61P29/00;C07D211/58;C07D243/08;C07D401/14;C07D403/06;C07D403/14;C07D413/14 |
主分类号 |
C07D401/04 |
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