发明名称 |
ANTIDOTES FOR AGONISTIC APTAMERS |
摘要 |
<p>The present invention relates, in general, to aptamers and antidotes therefor and, in particular, to aptamers capable of binding to and activating molecules, such as receptors (e.g., the OX40 receptor) and enzymes. The invention further relates to antidotes to such agonistic aptamers. The invention also relates to compositions comprising, and to methods of using, the agonistic aptamers and the antidotes therefor.</p> |
申请公布号 |
WO2009045545(A2) |
申请公布日期 |
2009.04.09 |
申请号 |
WO2008US11531 |
申请日期 |
2008.10.06 |
申请人 |
DUKE UNIVERSITY;SULLENGER, BRUCE;DOLLINS, CLAUDIA;GILBOA, ELI |
发明人 |
SULLENGER, BRUCE;DOLLINS, CLAUDIA;GILBOA, ELI |
分类号 |
A61K48/00 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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