Syringe for taking samples of body fluid for analysis has a connecting system (18) for attaching a single-use sampling unit (14) to the plunger (20). Independent claims are also included for: (a) a similar syringe in which the sampling unit is fitted with a sampling needle (58); (b) a portable diagnostic apparatus incorporating the syringe; (c) taking samples of body fluid for analysis using the syringe; and (d) apparatus for taking samples of body fluid for analysis using disposable test units in which the sample is taken using a needle.