发明名称 |
DNA SEQUENCE, AND RECOMBINANT PREPARATION OF THE GRASS POLLEN ALLERGEN LOL P 4 |
摘要 |
The present invention relates to the provision of a DNA sequence of the major grass pollen allergen Lol p 4. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilised for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for in vitro and in vivo diagnosis of pollen allergies.
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申请公布号 |
US2010310472(A1) |
申请公布日期 |
2010.12.09 |
申请号 |
US20100833235 |
申请日期 |
2010.07.09 |
申请人 |
NANDY ANDREAS;FIEBIG HELMUT;CROMWELL OLIVER |
发明人 |
NANDY ANDREAS;FIEBIG HELMUT;CROMWELL OLIVER |
分类号 |
A61K39/35;A61K38/16;A61K39/00;A61K49/00;A61P37/08;C07H21/04;C07K14/415;C12N1/21;C12N15/63;C12P21/06;G01N33/53 |
主分类号 |
A61K39/35 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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