发明名称 |
Compositions and Methods for Reducing the Toxicity of Certain Toxins |
摘要 |
Compositions and methods for reducing the toxic effect of certain peptide toxins by administering an agent that directly or indirectly reduces disulfide bonds that are important for maintaining the toxin in an active conformation. Also described are compositions and methods for reducing the toxic effect of toxins that contain a heavy metal using an agent that destabilizes the binding of a metal ion that is important for toxin activity.
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申请公布号 |
US2010310541(A1) |
申请公布日期 |
2010.12.09 |
申请号 |
US20080601994 |
申请日期 |
2008.05.27 |
申请人 |
IRONWOOD PHARMACEUTICALS, INC. |
发明人 |
KESSLER MARCO;CURRIE MARK G.;BUSBY ROBERT |
分类号 |
A61K38/44;A61K31/095;A61K33/04;A61K38/06;A61P29/00;A61P31/00;A61P31/04 |
主分类号 |
A61K38/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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