| 发明名称 |
SMALL MOLECULE INHIBITORS OF POLYNUCLEOTIDE KINASE/PHOSPHATASE, POLY(ADP-RIBOSE) POLYMERASE AND USES THEREOF |
| 摘要 |
<p>The present invention generally relates to use of compounds and compositions as a chemosensitizers and/or radiosensitizers and/or inhibitors of PNKP phosphatase activity. The present invention provides pharmaceutical combinations and/or a pharmaceutically acceptable salt thereof, kits containing such compounds and/composition and methods of using such compounds and/or compositions.</p> |
| 申请公布号 |
CA2764234(A1) |
申请公布日期 |
2010.12.09 |
| 申请号 |
CA20102764234 |
申请日期 |
2010.06.04 |
| 申请人 |
THE GOVERNORS OF THE UNIVERSITY OF ALBERTA;ALBERTA HEALTH SERVICES |
发明人 |
WEINFELD, MICHAEL;HALL, DENNIS G.;KARIMI-BUSHERI, FERIDOUN;FRESCHAUF, GARY KENNETH;MERENIUK, TODD RANDALL |
| 分类号 |
A61K31/437;A61K31/4745;A61N5/00;A61P35/00;C07D471/04;C12N9/14;C12N9/99 |
主分类号 |
A61K31/437 |
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