The present invention relates to a non-human transgenic animal whose genome comprises a stably integrated transgenic nucleotide sequence encoding Lysine-specific Demethylase 1 (LSD1 ) operably linked to a promoter. The invention further concerns methods for generating the non-human animal and its use as a cancer model.
申请公布号
WO2010139511(A1)
申请公布日期
2010.12.09
申请号
WO2010EP55720
申请日期
2010.04.28
申请人
UNIVERSITAETSKLINIKUM FREIBURG;SCHUELE, ROLAND;GUENTHER, THOMAS;METZGER, ERIC
