发明名称 PROCESS FOR HCV PROTEASE INHIBITOR INTERMEDIATE
摘要 <p>The present invention relates to a new process for the preparation of tripeptides of formula I wherein R1 is an amino protecting group and X is a halogen atom and wherein the tipeptide contains two olefinic moieties suitably disposed to undergo an intramolecular olefin metathesis reaction and produce macrocyclic tripeptides useful for the manufacture of macrocyclic HCV protease inhibitors.</p>
申请公布号 EP2150548(B1) 申请公布日期 2010.12.08
申请号 EP20080736214 申请日期 2008.04.15
申请人 F. HOFFMANN-LA ROCHE AG 发明人 GANTZ, FRANCOIS;STAHR, HELMUT
分类号 C07D403/12;C07D487/04 主分类号 C07D403/12
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