发明名称 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
摘要 The present invention encompasses novel antibodies and fragments thereof which immunospecifically bind to one or more RSV antigens and compositions comprising said antibodies and antibody fragments. The present invention encompasses methods preventing respiratory syncytial virus (RSV) infection in a human, comprising administering to said human a prophylactically effective amount of one or more antibodies or fragments thereof that immunospecifically bind to one or more RSV antigens, wherein a certain serum titer of said antibodies or antibody fragments is achieved in said human subject. The present invention also encompasses methods for treating or ameliorating symptoms associated with a RSV infection in a human, comprising administering to said human a therapeutically effective amount of one or more antibodies or fragments thereof that immunospecifically bind to one or more RSV antigens, wherein a certain serum titer of said antibodies or antibody fragments is achieved in said human subject. The present invention further encompasses compositions comprising antibodies or fragments thereof that immunospecifically bind to a RSV antigen, and methods using said compositions for detection or diagnosis a RSV infection.
申请公布号 US7847082(B2) 申请公布日期 2010.12.07
申请号 US20090476183 申请日期 2009.06.01
申请人 MEDIMMUNE, LLC 发明人 YOUNG JAMES F.;KOENIG SCOTT;JOHNSON LESLIE S.;HUSE WILLIAM D.;WATKINS JEFFREY D.;WU HERREN
分类号 C07H21/04;A61K39/155;A61K39/42;C07K16/10 主分类号 C07H21/04
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