SYNTHESIS OF 2-CYANOAZIRIDINE-1-CARBOXAMIDE

摘要

The present invention provides a process for producing an aziridine-1-carboxamide of the formula: (I) from an aziridine of the formula: (II) and an isocyanate of the formula R5-N=C=O, where R1~, R2~, R3~, R4~ and R5~ are those defined herein. In addition, the present invention also provides a process for producing a 4-imino-1,3-diazabicyclo[3.1.0]-hexan-2-one of the formula: (a) from the aziridine-1-carboxamide of Formula (I).