发明名称 |
DNA sequence, and recombinant preparation of the grass pollen allergen Lol p4 |
摘要 |
The present invention relates to the provision of a DNA sequence of the major grass pollen allergen Lol p 4. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilized for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for in vitro and in vivo diagnosis of pollen allergies.
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申请公布号 |
US7846448(B2) |
申请公布日期 |
2010.12.07 |
申请号 |
US20040583093 |
申请日期 |
2004.12.01 |
申请人 |
MERCK PATENT GMBH |
发明人 |
NANDY ANDREAS;FIEBIG HELMUT;CROMWELL OLIVER |
分类号 |
A61K38/00;A01N37/18;A61K39/00;A61K39/35;A61K39/36;C07K1/00;C07K14/00;C07K14/415;C07K17/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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