发明名称 |
Enhanced drug delivery in transdermal systems |
摘要 |
A composition for transdermal administration resulting from an admixture includes: a therapeutically effective amount of a pharmaceutically active agent that includes a corresponding steroid and a steroid derivative; and a carrier for the pharmaceutically active agent. The steroid and the corresponding steroid derivative are present in a weight ratio of 10:1 to 1:10 steroid: corresponding steroid derivative. In a preferred embodiment ratio is 6:1 to 1:6. In a preferred embodiment, the corresponding steroid derivative is a steroid ester. In another preferred embodiment, the carrier is a polymer that includes a pressure-sensitive adhesive.
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申请公布号 |
US7846916(B2) |
申请公布日期 |
2010.12.07 |
申请号 |
US20020330279 |
申请日期 |
2002.12.30 |
申请人 |
NOVEN PHARAMACETICALS, INC. |
发明人 |
HOUZE DAVID |
分类号 |
A61K31/56;A61K9/00;A61K9/70;A61K31/403;A61K31/565;A61K31/567;A61K31/5685;A61K31/57;A61K31/573;A61K38/55;A61K45/00;A61K45/06;A61K47/10;A61K47/12;A61K47/32;A61K47/34;A61K47/48;A61P5/26;A61P5/30;A61P9/12;A61P43/00 |
主分类号 |
A61K31/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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