发明名称 |
Melanoma associated peptide analogues and vaccines against melanoma |
摘要 |
The present invention is concerned with cancer treatment and diagnosis, especially with melanoma associated peptide analogues with improved immunogenicity, epitopes thereof, vaccines against melanoma, tumor infiltrating T lymphocytes recognizing the antigen and diagnostics for the detection of melanoma and for the monitoring of vaccination. The peptides according to the invention can be exploited to elicit native epitope-reactive Cm. Usage of the peptides with improved immunogenicity may contribute to the development of CTL-epitope based vaccines in viral disease and cancer.
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申请公布号 |
US7846450(B2) |
申请公布日期 |
2010.12.07 |
申请号 |
US20080337834 |
申请日期 |
2008.12.18 |
申请人 |
UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
FIGDOR CARL GUSTAV;ADEMA GOSSE JAN |
分类号 |
A61K39/00;A61K38/00;C07K14/47;C07K16/30 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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