| 发明名称 |
Antibodies against ErbB3 and uses thereof |
| 摘要 |
The present invention provides a novel class of monoclonal antibodies which bind ErbB3 receptor and inhibits various ErbB3 functions. In a particular embodiment, the antibodies are capable of binding to ErbB3 and inhibiting ligand mediated phosphorylation of the receptor.
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| 申请公布号 |
US7846440(B2) |
申请公布日期 |
2010.12.07 |
| 申请号 |
US20080281925 |
申请日期 |
2008.02.15 |
| 申请人 |
MERRIMACK PHARMACEUTICALS, INC. |
发明人 |
SCHOEBERL BIRGIT;NIELSEN ULRIK;FELDHAUS MICHAEL;MURUGANANDAM ARUMUGAM;BUCKLER DAVID |
| 分类号 |
A61K39/395;A61P35/00;C07K16/18 |
主分类号 |
A61K39/395 |
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