发明名称 |
USE OF MICROVESICLES IN DIAGNOSIS, PROGNOSIS AND TREATMENT OF MEDICAL DISEASES AND CONDITIONS |
摘要 |
The presently disclosed subject matter is directed to methods of aiding diagnosis, prognosis, monitoring and evaluation of a disease or other medical condition in a subject by detecting a biomarker in microvesicles isolated from a biological, sample from the subject. Moreover, disclosed subject matter is directed to methods of diagnosis, monitoring a disease by determining the concentration of microvesicles within a biological sample; methods of delivering a nucleic acid or protein to a target all by administering microvesicles that contain said nucleic acid or protein; methods for performing a body fluid transfusion by introducing a microvesicle-free or microvesicle enriched fluid fraction into a patient. |
申请公布号 |
KR20100127768(A) |
申请公布日期 |
2010.12.06 |
申请号 |
KR20107019343 |
申请日期 |
2009.02.02 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
SKOG JOHAN KARL OLOV;BREAKEFIELD XANDRA O.;BROWN DENNIS;MIRANDA KEVIN C.;RUSSO LEILEATA M. |
分类号 |
C12Q1/68;A61K9/133;A61K48/00;C12N15/11 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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