发明名称 |
2-METHYLENE-5-SUBSTITUTED METHYLENE CYCLOPENTANONE DERIVATIVES AND USE THEREOF |
摘要 |
<p>The invention relates to 2-methylene-5-substituted-methylenecyclopentanone derivatives of formula I, and the use thereof. The derivatives of formula I as active components are useful for preparing a medicine for the treatment and/or prevention of cancer diseases such as breast cancer, lung cancer, colon cancer, rectal cancer, stomach cancer, prostate cancer, bladder cancer, uterus cancer, pancreatic cancer and ovary cancer. The active compounds of the invention may be used as an anticancer drug alone or used in combination with one or more other antitumor drugs. A combined therapy can be carried out by administrating each therapeutic component concurrently, subsequently or separately.</p> |
申请公布号 |
EP2248796(A1) |
申请公布日期 |
2010.11.10 |
申请号 |
EP20090710520 |
申请日期 |
2009.02.10 |
申请人 |
SHENYAND PHARMACEUTICAL UNIVERSITY |
发明人 |
ZHAO, LINXIANG;WANG, JINGLI;BIAN, ZHENJUN;WANG, RUI;LIU, DAN;JING, YONGKUI |
分类号 |
C07C49/687;A61K31/122;A61P35/00;C07C45/59;C07C45/67;C07C49/653;C07C49/683;C07C49/697;C07C49/753;C07C225/22;C07C317/24;C07D317/54;C07D317/64 |
主分类号 |
C07C49/687 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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