发明名称 |
METHOD AND KIT FOR THE DETECTION OF GENES ASSOCIATED WITH PIK3CA MUTATION AND INVOLVED IN PI3K/AKT PATHWAY ACTIVATION IN THE ER-POSITIVE AND HER2-POSITIVE SUBTYPES WITH CLINICAL IMPLICATIONS |
摘要 |
<p>A method to determine the clinical outcome of breast tumor affecting a patient if treated with an antitumoral agent against breast tumor. The method includes the step of assaying a sample of a breast tumor from the patient for an expression level of selected genes, by contacting mRNA sequences from the cells of this breast tumor with a set of more than 3 nucleotide sequences related to human mutated PIK3CA.</p> |
申请公布号 |
EP2247756(A2) |
申请公布日期 |
2010.11.10 |
申请号 |
EP20090712209 |
申请日期 |
2009.02.20 |
申请人 |
UNIVERSITE LIBRE DE BRUXELLES |
发明人 |
SOTIRIOU, CHRISTOS;LOI, SHERENE;MC ARTHUR, GRANT;HAIBE-KAINS, BENJAMIN |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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地址 |
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