| 发明名称 |
Glycosylated antibodies |
| 摘要 |
The invention provides an antibody of human IgG1 or IgG3 type being glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is at least 99%, and in addition the amount of NGNA is 1% or less and/ or the amount of N-terminal alpha 1,3 galactose is 1% or less, and uses thereof. |
| 申请公布号 |
EP2248831(A1) |
申请公布日期 |
2010.11.10 |
| 申请号 |
EP20100166861 |
申请日期 |
2007.04.10 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
HANSEN, SILKE, DR.;KUENKELE, KLAUS-PETER, DR.;REUSCH, DIETMAR;SCHUMACHER, RALF, DR. |
| 分类号 |
C07K16/28;A61K39/395;A61P35/00;A61P37/00;C12P21/00 |
主分类号 |
C07K16/28 |
| 代理机构 |
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代理人 |
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| 地址 |
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