发明名称 |
METHOD FOR PRODUCTION OF LAUROLACTAM |
摘要 |
<p>Disclosed is a method for producing laurolactam from cyclododecanone and hydroxylamine in a simple process and with high efficiency. The method comprises the following steps (a) to (e): (a) reacting cyclododecanone with hydroxylamine in an aqueous solution in the presence of an excess amount of cyclododecanone or a solvent to produce cyclododecanone oxime; (b) separating the reaction mixture obtained after the oxime-forming step into an oil and an aqueous phases and collecting a solution of cyclododecanone oxime of the oil phase as; (c) removing dissolved water from the solution of cyclododecanone oxime which is collected as an oily phase in the oil/aqueous phase separation step; (d) producing laurolactam from cyclododecanone oxime by rearrangement reaction using an aromatic-ring containing compound as a rearrangement catalyst; and (e) separating the produced laurolactam from the reaction mixture after the rearrangement step and purifying the laurolactam.</p> |
申请公布号 |
EP2123635(A4) |
申请公布日期 |
2010.11.10 |
申请号 |
EP20080711071 |
申请日期 |
2008.02.08 |
申请人 |
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY;UBE INDUSTRIES, LTD. |
发明人 |
ISHIHARA, KAZUAKI;KUGIMOTO, JUNICHI;KAWAI, JOJI |
分类号 |
C07D201/04;C07B61/00;C07D225/02 |
主分类号 |
C07D201/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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