AN ENGINEERED CXCL12 ALPHA LOCKED DIMER POLYPEPTIDE
摘要
The present invention provides a novel CXCL12-α2 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS.
申请公布号
EP2247302(A1)
申请公布日期
2010.11.10
申请号
EP20090716023
申请日期
2009.02.26
申请人
MCW RESEARCH FOUNDATION, INCORPORATED;THE ROCKEFELLER UNIVERSITY
发明人
VOLKMAN, JAMES, B.;VELDKAMP, CHRISTOPHER, T.;PETERSON, FRANCIS, C.;SAKMAR, THOMAS;SEIBERT, CHRISTOPH, H.