| 摘要 |
THE PRESENT INVENTION PROVIDES A METHOD FOR IMPROVING THE BIOAVAILABILITY OF A RENIN INHIBITOR PREFERABLY, OF A @-AMINO-@-HYDROXY-@-ARYL-ALKANOIC ACID DERIVATIVE, WHICH METHOD COMPRISES CO-ADMINISTERING TO A MAMMAL, ESPECIALLY A HUMAN, IN NEED OF SUCH A TREATMENT, A COMBINATION OF A RENIN INHIBITOR, OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND AN EFFLUX PROTEIN INHIBITOR.
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