| 发明名称 |
Stabilized liquid polypeptide-containing pharmaceutical compositions |
| 摘要 |
Stabilized liquid polypeptide-containing pharmaceutical compositions are provided. The compositions comprise an amino acid base, which serves as the primary stabilizing agent of the polypeptide, and an acid and/or its salt form to buffer the solution within an acceptable pH range for stability of the polypeptide. Methods for increasing stability of a polypeptide in a liquid pharmaceutical composition and for increasing storage stability of such a pharmaceutical composition are also provided.
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| 申请公布号 |
US7807142(B2) |
申请公布日期 |
2010.10.05 |
| 申请号 |
US20050293322 |
申请日期 |
2005.12.05 |
| 申请人 |
NOVARTIS VACCINES AND DIAGNOSTICS, INC. |
发明人 |
CHEN BAO-LU;HORA MANINDER S. |
| 分类号 |
A61K9/08;A61K45/00;A61K9/14;A61K9/20;A61K31/195;A61K38/00;A61K38/20;A61K38/21;A61K38/57;A61K47/04;A61K47/12;A61K47/18;A61K47/20;A61K47/34;A61K49/00;A61P17/06;A61P19/02;A61P25/00;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P29/00;A61P31/18;A61P35/00;A61P37/06;A61P43/00;C07K1/02 |
主分类号 |
A61K9/08 |
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